Sotorasib (Lumakras,Sotoldx)

Sotorasib covalently binds to the switch pocket of KRAS G12C mutant protein, specifically inhibits GTPase activity and blocks abnormal RAS signaling.

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Sotorasib Medication Q&A

How effective is Lumakras, and what is its survival rate?

In one clinical trial of Lumakras, 45 out of 124 patients (36%) experienced either complete disappearance or a reduction of at least 30% in the size o···【More】
Update: 19 Mar,2026Source: BigbearViews: 92
How should I store sotorasib?

Store sotorasib at room temperature between 68°F and 77°F (20°C to 25°C).This bottle is equipped with a child‑resistant cap.Keep this medicine out of ···【More】
Update: 19 Mar,2026Source: BigbearViews: 95
Which other medications may affect sotorasib?

Inform your healthcare provider about all medications you are taking, including prescription drugs, over‑the‑counter medicines, vitamins, dietary supp···【More】
Update: 19 Mar,2026Source: BigbearViews: 98
What if I miss a dose?

If you forget to take a dose of sotorasib, take it as soon as you recall. If more than 6 hours have passed, skip the missed dose. Take your next dose ···【More】
Update: 19 Mar,2026Source: BigbearViews: 93